Pet Health
· Updated March 02, 2026· 6 min read

How Glandex Works: Benefits for Anal Gland Problems in Dogs and Cats

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Vetnique Team
Written by Vetnique Team
Last medically reviewed: March 02, 2026
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- Glandex is a veterinarian-formulated supplement designed to support healthy anal gland function by promoting firm, well-formed stools that naturally express the glands during bowel movements
- The patented formula combines high-quality fiber from pumpkin seed and apple pectin to bulk up stool so the anal glands are expressed normally with each defecation
- Anti-inflammatory ingredients including quercetin dihydrate and bromelain help reduce irritation in dogs with chronic anal gland problems or underlying allergies contributing to the issue
- Lactobacillus acidophilus is included as a probiotic to support digestion and immune function, which plays a role in overall anal gland health
- Most pet parents see results within 3 to 5 weeks when Glandex is given as directed — it is available as a peanut butter flavored chew that dogs love, as well as powder formulas for picky eaters
- Glandex Wipes provide a convenient one-step solution for cleaning the anal area after expression or when odor is present, using Deoplex enzymatic deodorizer along with vitamin E, aloe, and skin conditioners

Impacted or infected anal glands can be a painful and expensive problem for dogs, cats, and their owners. When the anal glands are not emptying properly on their own, finding a product that supports healthy natural expression can be a turning point for pets dealing with this issue.

Glandex is a veterinarian-formulated supplement designed to help pets who are having trouble expressing their anal glands normally. Its patented formula promotes healthy stools and supports normal expression of the anal gland material — addressing the root cause of most anal gland problems rather than just managing symptoms.

What Are Anal Glands and Why Do They Get Impacted?

Anal glands are two small structures located on either side of the anus. They expel a small amount of scent-marking fluid each time an animal has a bowel movement — this is how dogs and cats communicate territory and identity to other animals.

The key to healthy anal gland function is stool consistency. When stools are firm and well-formed, they put adequate pressure on the glands as they pass through the rectum, causing the glands to empty naturally. When stool consistency is not ideal — too soft, too loose, or inconsistent — the glands do not receive enough pressure. The fluid inside gets backed up and begins to thicken. Once the liquid has thickened, it cannot escape through the small ducts, and the gland can quickly become painful, impacted, or infected.

For a complete overview of anal gland anatomy, symptoms, and treatment, see our in-depth guide on anal gland issues in dogs.

Diagram showing anal gland anatomy and location in dogs

How Glandex Works

Glandex takes a three-pronged approach to anal gland support: high-quality fiber to improve stool consistency, anti-inflammatory ingredients to reduce gland irritation, and probiotics to support overall digestive health. Here is how each component contributes to healthy anal gland function.

Fiber for healthy stool quality

The foundation of Glandex's formula is high-quality fiber from two key ingredients. Pumpkin seed provides an ideal source of both soluble and insoluble fiber, and apple pectin contributes additional soluble fiber. Together, these ingredients help bulk up the stool so that adequate pressure is applied to the anal glands during each bowel movement, promoting consistent natural expression.

This is the most important piece of the puzzle — when stool quality improves, the anal glands are far more likely to empty on their own without the need for manual intervention.

Glandex supplement ingredients including pumpkin seed and natural fiber sources

Anti-inflammatory ingredients for gland irritation

For dogs with chronic anal gland problems or underlying allergies contributing to persistent irritation, Glandex includes targeted anti-inflammatory ingredients.

Quercetin dihydrate is a flavonoid found in many fruits and vegetables that provides powerful antioxidant, anti-inflammatory, and antihistamine properties. Bromelain is an enzyme extracted from pineapple that increases the bioavailability of quercetin while also supporting digestion and reducing inflammation. Together, these ingredients help calm irritated glands and address the allergic and inflammatory responses that often contribute to chronic anal gland issues.

Probiotics for digestive and immune health

Glandex includes Lactobacillus acidophilus, a well-studied probiotic that supports healthy digestion and immune function. A balanced gut microbiome contributes to consistent stool quality, which in turn supports the natural anal gland expression process. Probiotic support also helps dogs whose anal gland problems are connected to broader digestive issues.

Glandex's Patented Formula: What to Expect

Glandex's patented formula is designed to be a more sustainable and comfortable approach to anal gland health than frequent manual expression. Repeated manual expressing can actually irritate the glands further, creating a cycle of recurring problems. By supporting the body's natural expression process through improved stool quality and reduced inflammation, Glandex helps break that cycle.

Most pet parents see results within 3 to 5 weeks when Glandex is given as directed. Glandex contains all natural, premium ingredients and is made in the USA.

Glandex Soft Chews come in a peanut butter flavor that dogs love and are the most popular option for general anal gland support. For dogs with more severe or chronic issues, Glandex Advanced Vet Strength Chews provide a higher-potency formula. Dogs whose primary concern is digestive health and stool quality can benefit from Glandex Probiotic & Prebiotic Soft Chews.

For picky eaters who will not take chews, Glandex Powder can be mixed directly into food. An Advanced Vet Strength Powder is also available for pets with more persistent issues. Glandex is available for both dogs and cats.

Glandex Wipes for Daily Hygiene

Alongside the Glandex supplement line, Glandex Wipes provide a convenient one-step solution for keeping the anal area clean. These wipes are designed for use after anal gland expression or whenever odor is present due to anal gland irritation.

Glandex Wipes contain Deoplex, an enzymatic deodorizer that breaks down anal gland odor at the molecular level. They also include vitamin E, aloe, skin conditioners, and moisturizers to soothe the area, along with a light fresh scent to keep pets smelling their best.

Explore the full range of anal gland support products in the Glandex collection.

For more on the basics of anal gland anatomy and function, see our quick facts about anal glands in dogs and cats. For a comprehensive guide to anal gland problems including causes, symptoms, and treatment, visit our resource on anal gland issues in dogs.

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VETNIQUE TEAM SAYS
"Glandex works by addressing the root cause of most anal gland problems — stool quality. Its patented blend of fiber, anti-inflammatory ingredients, and probiotics promotes firm, well-formed stools that naturally express the anal glands during bowel movements, reducing the need for frequent manual expression."
— Vetnique Team

Frequently Asked Questions

How does Glandex work?

Glandex works by promoting firm, well-formed stools that put adequate pressure on the anal glands during bowel movements, allowing them to empty naturally. The patented formula combines high-quality fiber from pumpkin seed and apple pectin to improve stool consistency, anti-inflammatory ingredients to reduce gland irritation, and probiotics to support healthy digestion. By addressing stool quality — the root cause of most anal gland problems — Glandex reduces the need for frequent manual expression.

What are the key ingredients in Glandex?

Glandex contains pumpkin seed and apple pectin as sources of soluble and insoluble fiber to bulk up stool. Quercetin dihydrate is a flavonoid with antioxidant, anti-inflammatory, and antihistamine properties. Bromelain is an enzyme from pineapple that increases quercetin bioavailability and supports digestion. Lactobacillus acidophilus is a probiotic that supports digestion and immune function. All ingredients are premium quality and the product is made in the USA.

How long does it take to see results with Glandex?

Most pet parents see results within 3 to 5 weeks when Glandex is given as directed. Consistency is important — daily supplementation allows the fiber, anti-inflammatory, and probiotic ingredients to build up their beneficial effects on stool quality and digestive health over time.

Is Glandex available for cats?

Yes. Glandex is available for both dogs and cats. Cats have the same anal gland anatomy as dogs and can develop the same types of problems, so they benefit from the same approach of supporting firm stools and healthy digestion.

What forms does Glandex come in?

Glandex is available as soft chews in a peanut butter flavor that most dogs love, as well as powder formulas that can be mixed into food for picky eaters. Both chew and powder options are available in standard and Advanced Vet Strength formulas. A probiotic and prebiotic formula is also available for dogs whose primary concern is digestive health and stool quality.

What are Glandex Wipes used for?

Glandex Wipes are designed for cleaning the anal area after anal gland expression or when odor is present due to anal gland irritation. They contain Deoplex, an enzymatic deodorizer that breaks down odor at the molecular level, along with vitamin E, aloe, skin conditioners, and moisturizers to soothe the area. They provide a convenient one-step cleaning solution for day-to-day anal gland hygiene.

Why is Glandex better than frequent manual anal gland expression?

Frequent manual expressing of the anal glands can lead to further irritation and inflammation, creating a cycle of recurring problems. Glandex addresses the root cause — stool quality and digestive health — so the glands can empty naturally during normal bowel movements. This is generally easier on both pets and owners than repeated trips for manual expression.

Can Glandex help if my dog already has anal gland problems?

Glandex is formulated to support dogs that are already having trouble expressing their anal glands normally. By improving stool consistency and reducing gland irritation, it helps promote healthy natural expression. For dogs with more severe or chronic anal gland issues, Glandex Advanced Vet Strength formulas provide a higher-potency option. If your dog has an active infection, abscess, or rupture, consult your veterinarian for treatment before starting supplementation.

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Veterinary Disclaimer

Vetnique Labs was founded by Dr. James Bascharon, DVM, and all content is reviewed by our Vet Advisory Board. This information is not a substitute for professional veterinary advice. Always consult your veterinarian.

Vetnique Team
About the Author

Vetnique Team

The pet health and wellness team at Vetnique. Backed by veterinary science and dedicated to helping pet parents keep their dogs and cats happy and healthy.

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