About Glandex - Best Anal Gland Supplement for Dogs and Cats
Boot The Scoot!™
Medically reviewed by James Bascharon, DVM | Last reviewed: April 2026
Veterinarians and pet owners everywhere know Glandex® as the most effective way to maintain healthy anal glands in dogs and cats. That's because Glandex is the only product that supports all of the underlying causes and works from the inside out to keep the anal glands healthy.
Glandex is an oral supplement specifically designed for dog and cat anal gland health. The patented scientific formula works on multiple fronts to keep the glands functioning normally — and it's a better long-term option than frequent manual expression, which often irritates the glands further.
The formula uses a unique fiber blend to promote bulky, firm stools, which support the natural emptying of the anal glands during every bowel movement. Glandex also contains omega fatty acids, probiotics, and digestive enzymes to support healthy anal glands and a healthy gastrointestinal tract — two systems that are more connected than most owners realize.
Glandex® Soft Chews — daily treat for dogs. Peanut butter and beef flavors. Recommended for dogs only.
Glandex® Advanced Vet Strength Chews — higher-potency formula for dogs with severe or chronic anal gland issues.
Glandex® Original Powder — sprinkles onto food. Suitable for dogs and cats. Ideal for picky eaters.
Glandex® for Cats — feline-specific daily probiotic powder. Tuna flavor. Given once daily mixed into food.
Below are answers to the most common questions about Glandex. If you have additional questions, contact us or call 800-643-7558.
Start at half the recommended amount for the first 5–7 days, then increase to the full recommended amount. This allows your pet's digestive system to adjust to the added fiber content. Jumping straight to the full amount can cause temporary soft stools or gas — a minor, preventable setback that puts a lot of owners off before they see results.
Glandex works from the inside out. The patented formula uses a unique fiber blend to promote bulky, firm stools, which apply natural pressure to the anal glands during defecation and help them empty on their own. The formula also contains omega fatty acids to support a healthy inflammatory response and maintain normal histamine levels, plus probiotics and digestive enzymes to support GI health. A healthy digestive tract directly supports healthy anal gland function — the two systems work together.
Yes. Glandex is safe with no known significant or long-term side effects. All ingredients are all-natural and vet-recommended. Mild effects when first starting — soft stools or mild GI upset — come from the increased fiber content and are easily avoided by starting at half the recommended amount for the first 5–7 days. Glandex is made in the USA at an FDA registered and cGMP compliant facility.
No known significant or long-term side effects. You may notice larger stools, which is normal and expected — it's the fiber doing its job. Mild, temporary effects when first starting (soft stools, gas, mild GI upset) come from the increased fiber content. Starting at half the recommended amount for the first 5–7 days prevents most of these, then gradually increase to the full amount.
Most pets see results within 3–5 weeks of consistent daily use. Some pets with more persistent issues may require up to 2–3 months to achieve optimal results. If you haven't seen improvement after several weeks, try increasing to twice the recommended amount — some pets need more fiber to respond.
Glandex is designed for ongoing daily use to maintain healthy anal gland function long term. It's safe to discontinue at any time, including if your pet no longer shows anal gland concerns.
Glandex Soft Chews: Give once daily as a treat, following the recommended amount by weight. Most dogs take them eagerly.
Glandex Powder: Sprinkle directly onto dry food once daily. Can also be mixed with a small amount of warm water to create a gravy. For picky eaters, mix into wet food, yogurt, cottage cheese, peanut butter, or another favorite. Can also be given directly into the mouth using a syringe with a small amount of water.
Daily amount and bottle size depend on your pet's weight. See the Glandex dosing guidelines for a full breakdown by pet size and product format.
Both contain the same active ingredients and work equally well. Soft Chews are treat format and recommended for dogs only. Powder sprinkles onto food and is suitable for both dogs and cats. Choose based on your pet's preference and ease of administration.
Glandex Powders contain 8 calories and 0.36 grams of fat per teaspoon serving (2.96 g).
Glandex Peanut Butter Soft Chews contain 13.7 calories and 0.54 grams of fat per 1 chew serving (4.0 g).
All sizes contain the exact same ingredients, concentration, and dosing. The only difference is the total amount of product in each bottle. Larger sizes offer better value for bigger pets or multi-pet households.
Yes. Glandex Feline Powder is specifically formulated for cats and comes in tuna flavor. Given once daily mixed into food using the recommended amount on the label. Glandex Soft Chews are for dogs only.
Yes. Glandex helps pets with leaking glands — where fluid discharges spontaneously between bowel movements. Leaking usually happens because the glands aren't emptying properly or because they're inflamed and over-secreting. Glandex addresses both mechanisms through fiber and anti-inflammatory ingredients.
Recommended but not required to have the glands emptied before starting Glandex. Intermittent or regular expression may still be needed depending on severity — Glandex supports natural emptying over time. If you suspect your pet's glands need attention, consult your veterinarian.
Alongside daily Glandex use: feed a high-quality diet free from excessive fillers to maintain firm stools; keep your pet at a healthy weight — overweight pets often struggle to empty their glands; provide regular exercise to strengthen the muscles involved in defecation; reduce exposure to known allergens if allergies contribute; and use Glandex Wipes for perianal hygiene and topical soothing with vitamin E and aloe.
Some pets need 2–3 months for full benefits. If you haven't seen improvement after several weeks, increase to twice the recommended amount — some pets need more fiber. If no improvement after 8–10 weeks at the higher amount, all Glandex products carry an unconditional 100% satisfaction guarantee and can be returned for a full refund within 90 days of purchase.
Browse the full Glandex anal gland health collection for supplements, wipes, sprays, and powders for dogs and cats.
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